RiboMed News 2004

Phoenix biotech firm gets grant to detect airborne pathogens

The Arizona Republic Mar. 24, 2004 Article by Jodie Snyder.

RiboMed receives $3 million in contracts to fight bioterrorism: Phoenix, Arizona (January 12, 2004) – RiboMed Biotechnologies, Inc. has just received over $3 million in contracts to use their RiboMakerâ Detection System in a portable sensor for germs used in bio warfare. Funds for the project come from the Defense Advance Research Projects Agency (DARPA) under the new HISSS Program (Hand-held Isothermal Silver Standard Sensor). The program will fund development and production of a hand-held device to be used by military personnel for rapid detection of infectious organisms, including deadly bacteria and viruses like anthrax and smallpox. The organisms will be detected using a novel process called abscription™, for abortive transcription, which was invented by RiboMed’s founder and CEO, Dr. Michelle Hanna. The process can be used to detect protein, DNA, and RNA molecules that are specifically associated with these different bio warfare agents.

The HISSS program is a scientific and engineering collaboration involving RiboMed and five organizations from outside Arizona. DARPA and the U.S. Army Soldiers Chemical and Biological Command (SBCCOM) will be funding and overseeing the project. The device will be built by Northrop-Grumman and will utilize sample preparation technologies developed by MFSI, DNA amplification technologies developed by Ionian Technologies, and RNA and protein detection technologies developed by RiboMed. Staff from each of the participating organizations will meet at RiboMed’s new facilities in Phoenix for a kickoff meeting on in January.

This $3 Million funds just the first 12 months of what is expected to be a 3.5 year project. In the first phase, RiboMed will focus on optimizing abscription for the detection of RNA viruses and protein toxins in solution. The Company will have fourteen scientists and researchers working on its portion of the project. During the second phase of the project, abscription will be adapted for use in a portable micro fluidic device.

The RiboMaker™ Detection System is a proprietary, specific and sensitive signal-generation technology that utilizes the Company’s RiboLogs® and isothermal abscription (abortive transcription) process. RiboMaker® is a versatile platform for the production of thousands to millions of signals from a single target nucleic acid or protein, without the use of PCR or gel electrophoresis, making it highly amenable to automated technologies and high throughput screening.

RiboMed Biotechnologies, Inc., was originally founded as Designer Genes in 1999 and is headquartered in Phoenix, Arizona. RiboMed develops technologies and reagents for the detection of RNA, DNA and protein and the analysis of SNPs and CpG methylation sites. RiboMed is dedicated to the early detection of diseases and the agents that cause them.

RiboMed Selected to Present at World’s Best Technologies 2005: Phoenix, Arizona (November 2004) – RiboMed Biotechnologies, Inc. has been pre-selected to present its signature RiboMaker® Detection System at the World’s Best Technologies 2005 Conference in Arlington, Texas in March of next year. The RiboMaker® Detection System is a robust, isothermal, PCR-free method for detecting and quantifying proteins and nucleic acids. The core signal-generation technology, Abscription™, utilizes the reiterative synthesis of short aborted RNA transcripts (Abscripts™) by RiboMaker® Abscriptase™ to generate thousands to millions of quantifiable signals from a single target nucleic acid or protein, making it highly amenable to automated technologies and high throughput screening.

RiboMed Biotechnologies, Inc. is a translational genomics company developing rapid, specific, and robust tests for the early detection and characterization of diseases and their causative agents and the screening of drugs for treatment.

RiboMed is dedicated to improving life through early disease detection, non-invasive monitoring, and patient-specific therapies.

RiboMed CEO Featured on BioTech Today Radio Show

San Diego, California (November 2004) – Dr. Michelle Hanna, Founder and CEO of RiboMed Biotechnologies, Inc. was interviewed on “BioTech Today,” hosted by Dr. David Lemberg and Sam Kephart. “BioTech Today” is a New Media Internet radio show, carried by World Talk Radio, helping to promote the success of the biotechnology and nanotechnology industries. The show provides a supportive conversational environment, allowing industry leaders to present their mission, message, and products to a wide-ranging and inclusive international audience.

RiboMed Biotechnologies, Inc. is a translational genomics company developing rapid, specific, and robust tests for the early detection and characterization of diseases and their causative agents and the screening of drugs for treatment.

RiboMed is dedicated to improving life through early disease detection, non-invasive monitoring, and patient-specific therapies.

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